Created By: James Mosley
I'm glad to hear that you are interested in glucose detection and our work.
A couple of items before I answer your questions. First, I worked on this project while in Professor Michael Strano's lab at MIT. I have since moved on from his lab and am no longer working in this field. His lab is continuing to work on glucose detection but I am not involved in that work. Second, the glucose sensing tattoo was an idea for how our novel sensor technology could be employed but we have not yet created a working tattoo with our sensor technology.
Now to answer your questions:
1.) How is the sensor able to monitor glucose?
-- When light (we planned on on using something similar to a laser pointer) is shone on the tattoo ink the ink glows (it is not visible to human eyes though). How bright the ink glows depends on the amount of glucose that is in the body. So for the device to be useful as a glucose monitor, there are two components that are needed. The first component is the tattoo itself. The second component is a monitor that would shine light on the tattoo and measure how bright the tattoo was. We envisioned that this would be a watch-like device that could easily be positioned over the tattoo.
2.) How is the sensor more accurate?
-- Current continuous glucose monitors require that the patient uses a finger-prick test to calibrate the sensor or verify that the sensor signal (usually electrical signal) is equal to a specific amount of glucose in the body. For these monitors the signal "drifts" over time and patients must re-calibrate their monitor at least once per day for as long as they use the device (which can typically only be for 7 days). Because of how our sensor is designed there is no signal "drift", and this calibration step is not necessary. So our device is more accurate because the signal will not "drift" and change over the lifetime of the device. A specific signal will always indicate a specific amount of glucose.
Hope these answers help.
On Apr 12, 2013, at 7:55 PM, James Mosley wrote:
Dear Dr. Barone,
My name is James Mosley. I am a freshman at Santiago High School in Corona, California. I am currently working on a research paper on glucose monitoring tattoos. I read an article from MIT that said that you were working on a new glucose monitor that didn’t need finger pricks and was more accurate. I was wondering how it was able to monitor glucose through the skin, and how it was more accurate.
Category: second semester report | Comments: 0 | Rate: