A2:
Just
over one percent of the population suffer from a very serious
neurological disorder known as "Paranoid Schizophrenia". Schizophrenia
is a syndrome caused by a combination of genetically obtained traits,
environmental factors, and a disorganized breakdown of thought
processes. People diagnosed with Schizophrenia usually
experience auditory as well as visual hallucinations, and often have
trouble distinguishing what's real and imaginary.
Schizophrenia has always been hard for people to understand. Even though
the first official record of "Schizophrenia" by name was written less
than 100 years ago, a description that matched the disorder was made in
1887, classified as a "discrete mental illness", and the same symptoms
were described as far back as ancient Egypt, in the "Book of Hearts" (A
book written to describe mental illnesses). In Egyptian times, people
with Schizophrenia were thought to be possessed by demons, and were
locked away or committed to deadly procedures, such as drilling holes in
patients heads to release the "evil spirits".[Anonymous 2010
1] Thankfully,
we possess a much clearer understanding of this disorder, and treat it
much differently. Today, scientists have discovered that Schizophrenia
is linked to a variety of rare genetic mutations, and can be inherited
from a first or second-degree relative. Those with a parent or sibling
that have Schizophrenia, have a ten percent chance of acquiring this
disorder, while those with an identical twin have a forty-five to sixty
percent chance of acquiring it.[Anonymous 2009
2] Though
there have been links to obtaining this syndrome genetically, it is not
caused by the genes themselves, "In fact, recent research has found
that people with schizophrenia tend to have higher rates of rare genetic
mutations. These genetic differences involve hundreds of different
genes and probably disrupt brain development."[Anonymous 2009
1]
In addition to genetic causes, environmental factors are also thought
to play a role in developing this disorder. "Exposure to viruses or
malnutrition before birth, problems during birth, and other not yet
known psychosocial factors" [Anonymous 2009
3]
may be included in the list of causes. Studies have also indicated that
patients with Schizophrenia have slight differences in brain function
and structure, such as larger fluid-filled cavities in the center of the
brain, and significantly less "grey matter" (parts of the brain that
are dormant or in-active) [Anonymous 2010 A
1]
After death, scientists also found that the actual brain tissue was
slightly different from those without Schizophrenia, they suggested that
these differences in cell tissue most likely occurred before birth.
[Anonymous 2009
4]
Theories presented have suggested that in the womb, things may go wrong
during brain development, which would account for the slight brain
differences. It was also presented that the reason why the disorder
might not hit until the patient's teens, is that the neurological and
body stresses from puberty may trigger the defective genes into
action.[Harrison 2008
1 2]
Another theory suggests that Schizophrenia is caused by an interaction
of infectious disease, such as viruses. Not only can viruses
(take out "can" )attack
parts of the brain and leave others intact, but they can also alter
processes in the brain without killing it, and they can even lay dormant
for many years, which would explain why the disorder doesn't usually go
into action until
your late teens.[Harrison, 2008 A
1] Interestingly
enough, this theory also states that patients who grow up with cats
around are for unknown reasons slightly more prone to this
disorder.[Harrison, 2008 A
2] Many sufficient explanations have surfaced on the disorder, and advances are being made even today.
When people are effected with Schizophrenia, they experience a wide
variety of symptoms and side effects. Some of these symptoms include
auditory and visual hallucinations, delusions, loss of appetite and
hygiene, depersonalization, depression, and social
withdrawal.[Dryden-Edwards 2009
1]
Hallucinations and delusions are of the most common symptoms.
Hallucinations are when the patient will see or hear things that appear
to be real perceptions to them, and hallucinations are beliefs based on
insane or incomplete thoughts. Patients effected with hallucinations
will often hear voices that are not actually there, and respond to them.
Other times they see things that are not there, such as distorted
figures or people. Delusions are a bit trickier, patients effected truly
believe things that make no sense based on false or made-up
information
(re-word this sentence. It sounds weird). They may feel like someone is trying to kill them
(take out comma) or
follow them
and in some cases they even believe people are trying to read
their thoughts. Many Schizophrenics will experience disorganized
thoughts or speech patterns, "and may become uninterested in daily
activities, such as bathing, grooming, or dressing".[Anonymous 2012
1]
In rarer cases, Schizophrenics may become violent and act out in a
malicious manner. Patients will also often feel disconnected from their
families and friends, and have a harder times experiencing joy or
pleasure. They go into a gloomy state of withdrawal and keep to
themselves.[Anonymous 2012
2] They
also tend to eat less healthy and have more issues with drugs and
smoking, which can also be triggers for Schizophrenic episodes. When the
patient experiences social withdrawal, their relationships with their
family members become
(take out the "s") drastically affected, and they often become
suspicious and hostile towards their loved ones.[Anonymous 2008 A
1]
Suicide attempts are much more common in Schizophrenic patients, and
they are more likely to take their lives.[Anonymous 2008 A
2]
"Schizophrenics will tend to turn to drugs or alcohol to relieve their
symptoms and self-medicate. This condition is known as dual diagnosis.
Heavy smokers with schizophrenia who turn to smoking for the same
purpose will in fact
(take out "will") reduce the ability of their medication to work
as cigarette smoke is known to reduce the effectiveness of such
medication" -[Anonymous 2008 A 3]
This link is not liked
Today, there is no known cure for Schizophrenia, but very effective
treatments therapies and medication are available, and new advancements
in early-detection and prevention is showing promising results.[Cannon
2013
1]
Currently patients are being treated with antipsychotic drugs, which
block a certain kind of dopamine receptor (neurotransmitters in the
vertebrate central nervous system). Blocking this receptor lessens the
severity of the patients hallucinations
.
About seventy percent of people
treated with antipsychotics show some improvement while ten to fifteen
percent show drastic improvement. However, the side effects include
weight gain and motor tension, and around four fifths of patients stop
responding to the drugs within the course of treatment.[Cannon 2013
2]
Once patients stop taking the medication, they have a seventy percent
chance of total psychotic relapse within the next few years,
and antipsychotics do not treat functional disabilities and therefore do
not help their social or occupational skills, making social withdrawal
a side effect of Schizophrenia that cannot be restored. Although a
complete cure does not exist, recovery is possible. Around twenty-five
percent of patients recover within the first ten ears and live fairly
normal lives or live independently.[Tracy 2012
1] "By utilizing multiple therapies and medication, recovery from schizophrenia is possible."[Tracy 2012
2]
Another advancement in treatment options was obtained when scientists
started investigating the neurotransmitter called the glutamate receptor
(Synaptic receptors located on the membranes of neuronal cells). They
believe that by changing this receptor, chemical reactions in the brain
can be carried out normally.[Chandna 2007
1]
New information was surfaced when they discovered that the current
treatment being used (blocking dopamine receptors), caused a number of
side effects and was even linked to early onset Parkinson's disease (a
disorder that leads to the deterioration of the central nervous
system).[Chandna 2007
2]
The research on the glutamate receptors provides hope for a future
early onset cure for Schizophrenia. Another study suggested that taking a
fish oil supplement before any symptoms of Schizophrenia may help
prevent psychosis. "Researchers tested the efficiency of taking
long-chain Omega-3 fatty acids for the prevention of psychotic
disorders. The results show that taking Omega-3 not only reduces the
risk psychotic disorders developing further but may also provide a
viable strategy of prevention in young children with a predisposition
for psychotic states."- [Anonymous 2013 B
1]
It was found that Omega-3 fatty acids reduced the number of young
adults who developed the disorder when distributed at random to an
experimental and control group. [Anonymous 2013 B
2]
Some say that medication is not the only way a mental illness should be
treated, and fish oil is a better, more natural alternative. Natural or
unnatural supplements are not the only way to recovery, support from
family and friends, and an un-hostile environment is also necessary.
While Schizophrenia is a unique disorder itself, its now being proven to
be linked to a number of other things. The first links found
genetically were between a number of other psychiatric disorders,
specifically bipolar disorder, which is a disorder that causes extreme
mood changes.[Cookson 2009
1]
It was also discovered that the genes most closely related to those of
Schizophrenia, were the genes linked to the immune system, which would
support the connection between viral infection and Schizophrenia. There
have even been studies of people being more prone to getting this
disorder if their mother had a viral illness while pregnant. [Cookson
2009
2]
"One hypothesis says schizophrenia can be seen as a type of auto-immune
disease, which develops in people who are genetically susceptible and
whose immune system is triggered by infection or other environmental
factors."-[Cookson 2009
3]
Another link to Schizophrenia is not genetic, but physical. It was
found that Schizophrenia was linked to violence. Until the early 1980's,
it was believed that Schizophrenics were no more likely to be violent
than the general population, but it is now accepted that people with
this syndrome are significantly more likely to be violent. [Walsh, 2012
1 2]
Drug use (cocaine, nicotine, amphetamines, PCP) was found to be an
affecting component of Schizophrenia as well, it was proven to reduce
the effectiveness of antipsychotic drugs, as well as worsen their
symptoms. It was also found that patients taking drugs are less likely
to follow their doctors treatment plans. [Anonymous 2006
1]
While the normal rate of the U.S smoking population is around
twenty-five to thirty percent, the number of Schizophrenic
nicotine-dependent people is three times as high, and withdrawal from
the drug can temporarily worsen their symptoms. [Anonymous 2006
2 4]
Food can also effect Schizophrenia
, patients commonly have low levels
of omega-3 and B vitamins
and certain foods that are rich in these
nutrients have been known to help lessen the symptoms of Schizophrenia
and nourish the brain.[Anonymous 2013
B]
Foods that are suggested to be avoided are fatty or oily foods,
lactose, and gluten, because antipsychotics cause the patients to gain
weight and obesity should be avoided. It was also proven that ingesting
lactose and gluten worsens the symptoms of Schizophrenia and also should
be avoided. The diet a Schizophrenic person eats does not really affect
them that drastically, but gluten is the most recommended to stay away
from. Schizophrenia was found to be linked to more than just mental
disorders, it was also found to be related to diabetes. Patients with
Schizophrenia actually were found to be more prone to Type 2 diabetes
(self inflicted loss of pancreas abilities), and have a higher risk of
abnormal glucose metabolism.[Anonymous 2009 C
1]
Although,
Schizophrenia is a disorder without a cure, there is hope. Recovery is
possible, we know how it works, and why it causes the things it does,
and new advancements are being made constantly. With early detection,
medication, and proper environment, we can beat Schizophrenia, and give
the mentally ill a reason to recover.
Put the period after the hyperlink. This was a very well written paper